A study from Université Laval has demonstrated that camu-camu extract can effectively reduce liver fat in patients with non-alcoholic fatty liver disease (NAFLD), a condition affecting over seven million people in Canada.
In a 12-week randomized clinical trial involving thirty participants, those taking camu-camu extract showed a 7.43% reduction in liver fat, while those given a placebo experienced an 8.42% increase. This results in a significant 15.85% difference between the two groups, according to André Marette, lead researcher and professor at the Institut universitaire de cardiologie et de pneumologie de Québec – Université Laval (IUCPQ).
The benefits of camu-camu are attributed to its polyphenols, which interact with the intestinal microbiota. “The microbiota metabolizes the large polyphenol molecules, breaking them down into smaller, absorbable forms that help reduce liver fat,” explains Marette. The team identified two potential mechanisms: reducing lipogenesis (the formation of lipid droplets) and enhancing lipid oxidation (degradation). These mechanisms likely contribute to the extract’s effectiveness.
Despite these promising results, variability in individual responses was observed. Marette suggests that differences in initial gut microbiota may influence how effectively polyphenols are metabolized. Future research could focus on modifying the microbiota to improve extract efficacy.
Camu-camu extract is available in capsule form, though Marette advises caution regarding the polyphenol content of commercial products, as they can vary. The potential for combining camu-camu with other polyphenol-rich fruits like cranberries to enhance effects is also under consideration.